Coach Felipe Contepomi on Thursday changed the lock pairing with Efrain Elias and Franco Molina coming in for the experienced duo of Guido Petti and Tomas Lavanini.
Petti is moved to the flank where he replaces Benjamin Grondona after last weekend’s 27-21 defeat in San Salvador de Jujuy by the Wallabies.
Pedro Delgado is in at tighthead prop in place of Francisco Moreno, who drops to the bench.
Santiago Carreras is switched to fullback to replace Geronimo Prisciantelli, with the inexperienced Nicolas Roger coming at flyhalf, pairing with Simon Benitez Cruz.
Two uncapped players – Facundo Cardozo and Mateo Soler – are named among the replacements. Cardozo was only promoted to the squad this week when Matias Moroni suffered a face injury.
Pablo Matera, winning his 126th cap, continues as captain in the absence of Julian Montoya, who is one of several overseas-based players unavailable for selection.
Argentina matchday squad:
Starters: 15-Santiago Carreras, 14-Rodrigo Isgro, 13-Lucio Cinti, 12-Faustino Sanchez Valarolo, 11-Ignacio Mendy, 10-Nicolas Roger, 9-Simon Benitez Cruz, 8-Joaquin Moro, 7-Guido Petti, 6-Pablo Matera (captain), 5-Franco Molina, 4-Efraín Elias, 3-Pedro Delgado, 2-Ignacio Ruiz, 1-Boris Wenger
Replacements: 16-Leonel Oviedo, 17-Mayco Vivas, 18-Francisco Moreno, 19-Tomas Lavanini, 20-Juan Martin Scelzo, 21-Facundo Cardozo, 22-Gonzalo Bertranou, 23-Mateo Soler
Australia matchday squad:
Starters: 15-Tom Wright, 14-Max Jorgensen, 13-Joseph-Aukuso Suaalii, 12-Len Ikitau, 11-Filipo Daugunu, 10-Ben Donaldson, 9-Ryan Lonergan, 8-Harry Wilson (captain), 7-Fraser McReight, 6-Rob Valetini, 5-Jeremy Williams, 4-Josh Canham, 3-Taniela Tupou, 2-Billy Pollard, 1-Angus Bell
Reserves: 16-Josh Nasser, 17-Aidan Ross, 18-Massimo de Lutiis, 19-Lukhan Salakaia-Loto Shaw, 20-Charlie Cale, 21-Kalani Thomas, 22-Carter Gordon, 23-Isaac Henry